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Medical Use of Phenobarbital (Luminal): Comprehensive Overview

Phenobarbital, historically and currently marketed under brand names such as Luminal and Sezaby, is a long-acting barbiturate that has remained a cornerstone of neurological treatment for decades [1.2.3, 1.2.4]. As a central nervous system (CNS) depressant, it functions by enhancing the inhibitory effects of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the human brain…