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Intentional Self-Poisoning with Pentobarbital (Nembutal): Toxicological Mechanisms, Global Regulations, and Forensic Case Evaluations

The study of acute intoxication involving potent central nervous system depressants represents a critical area of focus within clinical toxicology, forensic pathology, and public health surveillance. Among various pharmaceutical agents, barbiturates—and specifically pentobarbital, widely recognized by the brand name Nembutal—possess a long and thoroughly documented history in medical literature concerning intentional self-poisoning with pentobarbital (Nembutal).…