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Pentobarbital vs Modern Sedatives: Understanding the Evolution of Sleep and Sedation Medications
The history of pharmacology is marked by a continuous quest for compounds that can safely and effectively modulate the central nervous system. For much of the 20th century, barbiturates—including pentobarbital—stood as the gold standard for managing anxiety, insomnia, and seizures. However, the introduction of benzodiazepines and subsequent classes of sedative-hypnotics in the latter half of…